Pair I.and seven years of research

Because we knew not all anthocyanins are created equal, we set out to discover exactly which ones could provide the health benefits we wanted to target, and we were successful! Our groundbreaking research revealed that Cyanidin and Delphinidin are the two most effective anthocyanins at supporting better overall metabolic health. We also discovered that consuming the right amount can help provide further support, but the unfortunate reality is, globally, the average adult consumes less than 25 mg per day, which is not nearly enough. This required deeper investigative digging to determine the perfect formulation,
i.e., the best blend and the optimal amount. WHY YOU’LL LOVE IT
• Helps support metabolic health.** • Helps support core metabolism for improved well-being.**
• Helps support vital organ health including the liver
and heart.**
• Helps support a healthy inflammatory balance/immune
activity for healthy cellular function.**
• Helps promote a healthy microbiome for better gut health.**
• Helps improve the antioxidant defense system, reducing
oxidative stress.• Supports your body’ s own unique microbiome. • Helps maintain healthy blood glucose.
• Features ageLOC technology that targets your core

• Provides our exclusive ageLOC Meta anthocyanin blend,
standardized to 215 mg of anthocyanins per serving.
**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  1. Araújo J, Cai J, Stevens J. Prevalence of Optimal Metabolic
    Health in American Adults: National Health and Nutrition
    Examination Survey 2009–2016. Metab Syndr Relat Disord.
    2019;17(1):46–52. doi:10.1089/met.2018.0105
  2. Sebastian RS, Wilkinson Enns C, Goldman JD, et al. A New
    Database Facilitates Characterization of Flavonoid Intake,
    Sources, and Positive Associations with Diet Quality among
    US Adults. J Nutr. 2015;145(6):1239–1248. doi:10.3945/
  3. Azzini E, Giacometti J, Russo GL. Antiobesity Effects of
    Anthocyanins in Preclinical and Clinical Studies. Oxid Med
    Cell Longev. 2017;2017:2740364. doi:10.1155/2017/2740364
  4. Cremonini E, Mastaloudis A, Hester SN, et al. Anthocyanins
    inhibit tumor necrosis alpha-induced loss of Caco-2 cell
    barrier integrity. Food Funct. 2017;8(8):2915–2923.
  5. Cremonini E, Daveri E, Mastaloudis A, et al. Anthocyanins
    protect the gastrointestinal tract from high fat diet-induced
    alterations in redox signaling, barrier integrity and dysbiosis.
    Redox Biol. 2019;26:101269. doi:10.1016/j.redox.2019.101269
  6. Daveri E, Cremonini E, Mastaloudis A, et al. Cyanidin and
    delphinidin modulate inflammation and altered redox
    signaling improving insulin resistance in high fat-fed mice.
    Redox Biol. 2018;18:16–24. doi:10.1016/j.redox.2018.05.012
  7. Hester SN, Mastaloudis A, Gray R, Antony JM, Evans M,
    Wood SM. Efficacy of an Anthocyanin and Prebiotic Blend
    on Intestinal Environment in Obese Male and Female
    Subjects. J Nutr Metab. 2018;2018:7497260. Published 2018
    Sep 13. doi:10.1155/2018/7497260
  8. Yang L, Ling W, Du Z, et al. Effects of Anthocyanins on Cardiometabolic Health: A Systematic Review and MetaAnalysis of Randomized Controlled Trials. Adv Nutr.
    2017;8(5):684–693. Published 2017 Sep 15. doi:10.3945/

Gut check: intestinal unease getting you down? From aiding digestion to helping maintain your overall gut health, the microorganisms in your GI tract impact your wellness far beyond your stomach. Pharmanex Nu Biome helps support this vital intestinal balance* with a powerful dual-action solution of pre- and postbiotics, plus a healthy boost of caffeine for added energy.* All in a delicious powder mix-in, so you can quickly and conveniently support your intestinal microbiome and feel your best every day.
• Helps harness the benefits of a healthy microbiome
through a dual approach using pre- and postbiotics.*
• Supports a healthy balance of good and bad bacteria for
improved intestinal health.*
• Helps maintain healthy digestion.*
• Helps maintain healthy energy levels.*
• Supports your body’s important antioxidant network.*
• Free from artificial colors, flavors, and sweeteners.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease

  1. Pedret A, Valls RM, Calderón-Pérez L, et al. Effects of
    daily consumption of the probiotic Bifidobacterium animalis
    subsp. lactis CECT 8145 on anthropometric adiposity
    biomarkers in abdominally obese subjects: a randomized
    controlled trial. Int J Obes (Lond). 2019;43(9):1863–1868.
  2. Balaguer F, Enrique M, Llopis S, et al. Lipoteichoic acid
    from Bifidobacterium animalis subsp. lactis BPL1: a novel
    postbiotic that reduces fat deposition via IGF-1 pathway
    [published online ahead of print, 2021 Feb 23]. Microb
    Biotechnol. 2021;10.1111/1751–7915.13769.
  3. Yang J, Summanen PH, Henning SM, et al. Xylooligosaccharide supplementation alters gut bacteria in both
    healthy and prediabetic adults: a pilot study. Front Physiol.
    2015;6:216. Published 2015 Aug 7.
  4. Lin, S. H., L. M. Chou, Y. W. Chien, J. S. Chang and C.
    I. Lin (2016). “Prebiotic Effects of Xylooligosaccharides
    on the Improvement of Microbiota Balance in Human
    Subjects.” Gastroenterol Res Pract 2016: 5789232.
  5. Finegold, S. M., Li, Z., Summanen, P. H., Downes, J.,
    Thames, G., Corbett, K., et al. (2014). Xylooligosaccharide
    increases bifidobacteria but not lactobacilli in human gut
    microbiota. Food Funct. 5, 436–445.
  6. Gil MI, Tomás-Barberán FA, Hess-Pierce B, Holcroft DM,
    Kader AA. Antioxidant activity of pomegranate juice and
    its relationship with phenolic composition and processing.
    J Agric Food Chem. 2000;48(10):4581–4589.
  7. Harpaz E, Tamir S, Weinstein A, Weinstein Y. The effect
    of caffeine on energy balance. J Basic Clin Physiol Pharmacol. 2017;28(1):1–10. )

Free Register Wholesale price. Sponzor ID Alexander Vasko SK5500064.

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