Duan L, Zhao L, Liang C, Lu J, Gao L, Li G, Zhu JS. Improvement of exercise metabolism and carotenoidsantioxidant scores with CordyMax and LifePak in young Chinese elite athletes. FASEB J April 6, 2010 24:805.4Abstract provided below for your convenience can be found online atthefollowinghttp://www.fasebj.org/cgi/content/meeting_abstract/24/1_MeetingAbstracts/805.4?sid=5612edc2-ca96-42b2-9849-924abbea8f00
Cordyceps sinensis and its fermentation product, CordyMax (CM), are used for anti-aging and healthpreservation. We have reported CM’s anti-fatigue and endurance enhancement functions in multi-sportendurance Caucasians athletes (Chin J Clin Pharmacy 2007, 5:16). LifePak (LP) is enriched in carotenoids andantioxidant nutrients to improve antioxidant capability in young athletes (FASEB J 2009, 23:1007.3). We further tested the improvement of exercise metabolism and antioxidant capacity with CM and LP in a self-controlled trial in young Chinese elite athletes (n=25, 18.1 yrs on average) recruited from China bicycle teams. They received CM 3.18 g/day and LP 2 sachets/day for 6 wks. All subjects remained on the same diet plan and training intensity
during the study. Before and after the treatment, subjects performed graded exercise test on cycle ergometer and photonic assays for antioxidant scores. At a work load of 100W, 150W or 200W, RER were reduced significantly by 27%, 31%, & 36% (p<0.001), and blood lactate by 14%, 31% & 33%, and also reduced by 24% & 20% immediately and 3 min after exercise (p<0.05). VO2 peak, HR and O2 pulse were not changed in these elite athletes. Carotenoids antioxidant scores were increased by 21% (p=0.02). In conclusion, our data suggest benefits of CM-LP in improving antioxidant capacity and exercise metabolisms to enhance endurance capability and
reducing risks of exercise injury in Chinese elite athletes.
Li CL, Bi SX, Poole S, Smidt C, Zhu JS. Human Skin Carotenoids in 88,611 subjects measured by Biophotonic Scanner. Chinese Journal of Clinical Pharmacy 2006;15(2):124-125.
No online abstract available
Biophotonic Scanner was designed by use of a technique of Resonance Raman Spectroscopy, a non-invasive, easy-to-use tool to specifically determine skin antioxidant carotenoids. We examined skin carotenoids of 88,611 volunteers, and monitored changes in human skin carotenoids as a function of life styles and in response to daily consumption of fruits, vegetables, and a dietary supplement LifePak. We found that skin carotenoids presented as Biophotonic Scanner scores are significantly closely, positively correlated with serum carotenoids determined
by use of HPLC (n=1116, r2=0.704, p<0.001). Non-smokers and subjects with less sun-light exposure had significantly higher scores than those for cigarette smokers and former smokers and people with high exposure to sun light (p<0.001). The higher the BMI, the lower the scores (p<0.001), indicating diluted fat soluble carotenoids in the skin associated with increased body fat mass. The more daily consumption of fruits and vegetables and dietary supplements, the higher the scores (p<0.01). Daily LifePak intake resulted in increases in the scores by
24.3% after 4 weeks of supplementation and by 44.0% after 8 weeks (p<0.001). In conclusion, Biophotonic scanner scores reflect steady state levels of antioxidant carotenoids in human’s skin. Fruits and vegetables intake and LifePak supplements increase the antioxidant capacity, but smoking and sun-light exposure reduce it.
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